HIGH RISK SCREENING PROTOCOLS

MRI Screening

ACRIN 6666 study of ultrasound screening in high risk women

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 HIGH RISK SCREENING PROTOCOLS

 

MRI Breast Screening Guidelines

NHSBSP PUBLICATION No 68 DECEMBER 2009

New NBS Guidelines for screening High Risk Women for Breast Cancer with Magnetic Resonance Imaging are being produced

The guidelines are not yet published on the NHS BSP website, but are available on our site and the NBSS

The latest documentation and forms can be found on the MRI page

Tittled - "technical guidelines for magnetic resonance imaging for the surveillance of women at increased risk of developing breast cancer"

The NHS Breast Screening Programme (NHSBSP) is responsible for setting and monitoring the standards for imaging surveillance of women below the screening age who are assessed as being at increased risk of developing breast cancer. This may be because of a family history of breast cancer or previous radiotherapy treatment for Hodgkin’s disease. The guidance sets out the technical standards required for the provision of breast MRI as part of the imaging surveillance of women at increased risk, and describes the arrangements for reporting MRI examinations and for quality assurance of MRI surveillance. The guidance is based on the results of the magnetic resonance imaging breast study (MARIBS)1 and has been compiled by a UK working party made up of members of the MARIBS steering group, representatives from industry including manufacturers of MRI equipment, and software companies producing tools for breast MRI analysis

DOCUMENTATION:

NHSBSP PUBLICATION No 68 DECEMBER 2009

REQUEST AND REPORTING FORM



ACRIN 6666 Study

Breast Ultrasound and Mammography in Screening Women at High Risk for Breast Cancer
Study closed for new subjects

ACRIN PROTOCOL 6666

American College of Radiology FAQs about the ACRIN 6666 study

NCI Summary Document

ACR, SBI Statement on ACRIN Breast Ultrasound Trial Results and Role of Ultrasound in Breast Imaging Care

The results of the American College of Radiology Imaging Network National Breast Ultrasound Trial (ACRIN 6666) demonstrated that a single screening ultrasound examination, added to a screening mammogram, increased detection of breast cancer compared with mammography alone, among women at increased risk of breast cancer who also had dense breast tissue. As is the case for other screening modalities, the ultimate utility of screening ultrasound depends on many other factors in addition to cancer detection, including the number of false positive findings resulting in the need for additional evaluations and benign biopsies, the availability of equipment, staff, and other resources necessary to perform the test on an appropriate scale, and its cost effectiveness

Papers and presentations produced so far: (RSNA 2009)

  1. Berg W, Zhang Z, Cormack J, Lehrer D, Bohm-Velez M, Pisano E, et al.
    Screening Breast Ultrasound as a Supplement to Mammography: Yield of Annual Screening in ACRIN 6666 
  2. Berg W, Zhang Z, Cormack J, Lehrer D, Bohm-Velez M, Pisano E, Jong R, Evans W, Morton M, et al.
    False Positives Induced by Annual Screening US Added to Mammography: ACRIN 6666 
  3. Berg W, Zhang Z, Cormack J, Jong R, Barr R, Lehrer D, et al.
    Supplemental Yield and Performance Characteristics of Screening MRI after Combined Ultrasound and Mammography: ACRIN 6666