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Hodgkin's Disease treated in young women

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INFORMATION SHEET
Breast Screening for Women at Increased Risk of Breast Cancer after Radiotherapy for Hodgkin’s Disease  

What’s The Purpose Of Screening?
The purpose of breast screening is to detect breast cancer as early as possible  by picking up changes to the breast that often cannot be seen or felt.  In the UK, around one in every 9 women will develop breast cancer at some point in their life-time (i.e. before 90years old). Women who received radiotherapy which included part of their breast tissue have a higher risk.  Early diagnosis of breast cancer offers the best chance of a successful recovery. It is not known whether or not breast screening is effective in women under 50 regardless of their risk. 

How does screening work?
X-ray pictures called mammograms are taken of the breast. Two views of each breast are taken at every screening appointment. Women having a mammogram are asked to undress to the waist, so wearing a separate top rather than a dress may be easier. The actual X-ray only takes a few minutes and the level of radiation is very low.

Who can have screening?


In the UK, all women aged 50 to 70 years are automatically invited for screening once every three years by the NHS Breast Screening Programme. Continued three yearly screening up to the age of 70 is available to those who want it.

Why does screening not start until the age of 50?

Research studies have shown that screening significantly reduces deaths from breast cancer in women aged 50-64 who attend for screening. For women under 50 the effectiveness of screening is controversial. Experts in the UK currently believe the disadvantages of screening outweigh the advantages for women in the general population under 50, hence it is not routinely offered.

Why am I being offered screening before I am 50?
For younger women who have an increased risk of developing breast cancer on account of their past medical history, the collective view of experts in the UK is currently that the benefits of screening are likely to outweigh the harms. However, it is important to realise that, as yet, there is no strong evidence to prove whether or not breast screening in younger women who received radiotherapy for Hodgkin’s Disease is effective and will reduce deaths from breast cancer.

Yes. We need to know whether screening women at higher risk works.

The Department of Health is planning to set up a national evaluation. For the purposes of this evaluation we need to hold personal information on you to issue regular invitations and to check on the performance of the programme. We take great care to keep your personal details confidential and only share information with people who have a statutory or medical requirement for it, for example your General Practitioner.



We are planning to centralise personal data from everyone involved in this evaluation. The data will be held in a database at the West Midlands Cancer Intelligence Unit which is based in Birmingham. These personal details will remain confidential. Only anonymised details will be released to the research teams involved in the evaluation.

Evaluation of the results will help the National Screening Committee to assess whether or not early screening is beneficial.

How reliable is screening?
Mammography is currently the best way of detecting breast cancer early. Early diagnosis offers the best chance of full recovery. Most cases of breast cancer detected early are successfully treated with the modern treatments now available. Screening does not prevent cancer and like most tests it is not perfect:  
  • Some cancers are very difficult to see on the X-ray
  • Some cancers, even though they are there, cannot be seen on the X-ray at all
  • The person reading the X-ray may miss the cancer (this will happen occasionally, no matter how experienced the reader is)
    Are other screening test available?   Yes. Magnetic Resonance Imaging (MRI) is also going to be offered to those women in whom we think Mammography will be hardest to interpret. So we are planning to offer MRI on its own to women aged between 25 and 29 and Mammography and MRI to women between 30 and 50 whose breasts are very ‘dense’ on x-ray. Like mammography, MRI is not perfect and to date there are no studies showing that screening with MRI reduces deaths.   Does Mammography hurt?   Each breast needs to be held firmly in position and compressed as the X-ray is taken, in order to obtain a clear picture.  Some women describe a mammogram as uncomfortable, while others describe it as painful.  Any discomfort only lasts for a few seconds.   Does MRI hurt?   No, but the machine is noisy and the room is small.   At what age does screening start for women who received radiotherapy for Hodgkin’s Disease?   This depends on the age you received Radiotherapy and will be tailored to your individual circumstances. Generally speaking at about 10 years after your radiotherapy but not before 25years old.   How often would I be screened?   Screening is currently recommended every year for younger women. This is because breast cancer in younger women may appear more quickly than in older women.     How would I get my results?   When you have had screening, a member of the screening team will tell you how and approximately when you will get your result.   What does it mean if I am called back for more tests?   Some women (about 1 in every 20 who goes for screening) are asked to come back for a further appointment because the appearance of the X-ray or MRI is not completely normal. It may be necessary to perform further mammographic views, or other investigations such as ultrasound or a biopsy may be needed. In the majority of cases, these further tests will show there is nothing to worry about.   What should I do if I notice any breast symptoms?   As breast cancer can occur between screening appointments it is important to see your doctor immediately if you notice any unusual changes in your breasts, even if you have just had a normal screen or are due for a screen in a month or so.   So should I go for screening or not?   To help you decide whether or not you want to attend for breast screening, the main advantages and disadvantages of regular screening in women under 50 are outlined below:   ·      Screening is believed to provide the best chance of detecting cancers at an early stage when treatment can be most successful. Currently there is no good evidence to prove this.
  • Around seventy per cent of the cancers found at screening are still small enough to be removed from the breast.  This means that the whole breast does not have to be removed.
  • Screening will not detect all breast cancers, so some cancers will be missed at screening and some women may be falsely reassured.
  • Screening will not prevent breast cancer from developing.
  • Approximately one in every 20 women who go for screening will be called back for further investigations.  Most of the women who have further tests will turn out not to have cancer.  However, women who are called back often find this a very anxious time.
  • Each mammogram gives a small dose of radiation.  The expert view is that the dose is so small it is unlikely to cause any harm and is at least 1,000 times smaller than the doses given for treatment.  However, it is theoretically possible that regular mammography in younger women could actually promote the development of a breast cancer.
  • Some women find mammography uncomfortable or painful.
  • Some women find MRI claustrophobic.
  What if I may be/am pregnant?   The radiation dose to the abdomen during mammography is extremely low, so you could still be screened. However, you may prefer to wait until you know you are not pregnant.   What do I do now?   If you would like further information about screening or would like to take up the offer of screening please contact your local breast screening unit whose details are at the bottom of this leaflet.   What if I do not want regular mammography?   You do not have to choose screening now. You will be invited automatically for screening after the age of 50 by the NHS Breast Screening Programme. If you change your mind before then and decide that you do wish to have screening please contact the person named below.     Further information about breast screening can be obtained from   Name   Address   Phone  between   x….y
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