UK FUNDED RESEARCH

 

 

 

 

 

Location

Investigator(s)

Funding Body

Title

Objective

Oxford, Manchester, UCL, ICR

JM Brady,CJ Taylor
SM Astley, D Hawkes,     MO Leach

EPSRC

A Model-based Approach to Comparing Breast Images

To develop computational methods to assist the radiologist in bilateral and temporal comparison of mammograms

UCL

SR Arridge

EPSRC

Parameter and Structure Indentification in Optical Tomography

Non invasive detection of breast tumours

Bristol

AW Preece
IJ Craddock

ESPRC

Enhanced UWB Radar Imaging of Breast Tumours

Development of new imaging method based on UWB radar to provide a cheap, quick and comfortable breast imaging method

Greenwich

Y Chen

ESPRC

Discrimination of Breast Lesions Using Ultra-wideband Microwave Imaging

To explore the influence of lesion morphology on backscatter microwave signature at each sensor of the imaging apparatus

Oxford

C Tromans

ESPRC

Characterising Features of Breast Tissue using Radiodensity Measured in X-Ray Mammograms and Tomosynthesis for Cancer Risk Assessment and Diagnosis.

Use of computer learning methods and a feature description vector to establish tissue features likely to develop cancer, to improve sensitivity and specificity of  CAD algorithms and tomosynthesis

Oxford

NP Hughes

ESPRC

Integrated Modelling of Functional Imaging and Gene Expression Data for Personalised Cancer Therapy

To develop new algorithms for "integrating" functional imaging and gene expression data to provide an improved prediction of the likely response to therapy.

Imperial College School of Medicine
London

 R Coombes

MRC

 

PET scans and response to treatment with docetaxel in early stage breast cancer

ICR

 S Moss

MRC

Effect on breast cancer mortality of annual mammographic screening starting at age 40

To determine the additional benefit of annual mammographic screening from age 40 rather than 50 in reducing deaths from breast cancer

Loughborough

A Feresidis

MRC

High-resolution microwave detection of tumours

Medical microwave imaging using novel near-field focusing plates

ICR

M Leach

MRC

Advancing the Application of Magnetic Resonance in Cancer: Structural, Functional and Molecular Studies of Tumours

3T clinical MRI scanner to add to existing state of art CT, PET-CT and SPECT facilities

Cambridge

N Walton

MRC

Astronomical Image Handling - Application to TMA Analysis: Exploiting AstroGrid/ CancerGrid Systems

To explore novel uses of techniques developed in the astronomical domain to provide solutions for
challenges inherent in the analysis and integration of large medical imagery

Aberdeen

A Welch

MRC

Transfer of fluorinase mediated C-18F bond formation technology to the clinical environment for tumor imaging by PET

To demonstrate that the fluorinase technology can be practically transferred to the clinical environment for clinical imaging

Guildford, London, Cambridge,

K Wells,  M Wallis,
R Given-Wilson, H Bosmans  

MRC/DH

OPTIMAM

Optimisation of breast cancer
detection using digital X-ray technology

Location

Investigator(s)

Funding Body

Title

Objective

Aberdeen

FJ Gilbert

HTA

Clinical effectiveness and cost-effectiveness of different surveillance mammography regimes after the treatment of primary breast cancer

To identify the most effective and efficient method of providing surveillance mammography for women who have previously been treated for primary breast cancer

Sheffield

School of Health and Related Research (ScHARR-TAG) 

HTA
Technology Assessment Report

Role of enhanced imaging techniques in the assessment of axillary lymph node metastases 

To assess diagnostic accuracy of different imaging technologies for the assessment of axillary lymph node metastases in patients with early stage breast cancer, and whether they can improve outcomes

Birmingham

West Midlands Health Technology Assessment Collaboration (WMHTAC)

HTA
Technology Assessment Report  

Systematic review of  PET and PET/CT for the diagnosis of breast cancer recurrence 

 

Hull

L Turnbull

CRUK

Neo-COMICE

Pilot study to establishing efficacy of advanced semi-automated f-MRI in the early prediction of response of locally advanced breast cancer to neoadjuvant chemotherapy

Institute of Cancer Research

J Bamber, N deSouza,       S Robinson

CRUK
Collaborative effort with 5 European partners from EU Framework 6 funding

Non-invasive molecular profiling of breast cancer with optoacoustic imaging.

Feasibility of optoacoustic molecular profile imaging of breast cancer using gold nanoparticles

 

 

CRUK

DETECT       

Development of biomarkers to improve outcomes for breast cancer patients at risk of bone metastases

Aberdeen
Glasgow
Dundee

FJ Gilbert

CSO

 

Multicentre study assessing the potential clinical application of FGD-PET/CT to the management of breast cancer, in particular, staging the axillary lymph nodes

Manchester

G Evans

Breast Cancer Campaign

FH02      

Mammographic surveillance in women aged 35-39 at enhanced familial risk of breast cancer (FH02)

LSHTM

V McCormack

Breast Cancer Campaign

Mammographic breast density in British young women: natural history and breast cancer prediction

To investigate how changes in breast density is related to a persons risk of developing breast cancer

Kings College Hospital, London

M Michell

NHSBSP

Breast Tomosynthesis

To determine whether 3D tomosynthesis imaging is more accurate than standard 2D mammography

UCL

MRS Keshtgar
S G Bown

US funded

Elastic Scattering Spectroscopy (ESS)

A trial testing a new type of biopsy for breast cancer using light measurements